The Serpent Queen is a period drama about Catherine de Medici, Renaissance Queen of France. Considered an immigrant, common and plain, Catherine de Medici is married into the 16th century French court as an orphaned teenager expected to bring a fortune in dowry and produce many heirs, only to discover that her husband is in love with an older woman, her dowry is unpaid and she's unable to conceive. Yet, only with her intelligence and determination, she manages to keep her marriage alive and masters the bloodsport that is the monarchy better than anyone else, ruling France for 50 years.